Author

J. Perrin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

A. Mourier· 1 shared A. Rutkowska· 1 shared B. Heller· 1 shared C. Barsa· 1 shared C. David· 1 shared C. E. Rau· 1 shared D. C. Sevin· 1 shared D. D. Childs· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Mourier

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2 papers

Recent·Most cited

A cellular assay to determine the fusion capacity of MFN2 variants linked to Charcot-Marie-Tooth type 2A

C. Barsa, J. Perrin, C. David, A. Mourier, M. Rojo

This paper develops a cellular assay to assess MFN2 variants' fusion capacity in CMT2A and shows correlation with computational predictions.

bioRxiv · Mar 11, 2024Cell Biology

Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo

J. Perrin, T. Werner, N. Kurzawa, D. D. Childs, M. Kalxdorf, A. Rutkowska, D. Poeckel, D. C. Sevin, E. Stonehouse, K. Strohmer, B. Heller, D. Thomson, J. Vappiani, J. Krause, H. C. Eberl, , G. Bergamini

This study introduces tissue-TPP and blood-CETSA to measure proteome thermal stability, revealing organ physiology and drug-target engagement in vivo.

bioRxiv · Dec 20, 2018 · PreprintCell Biology