Author

B. Heller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

A. B. Balazs· 1 shared A. Emili· 1 shared A. J. Trachtenberg· 1 shared A. K. O'Connell· 1 shared A. Klose· 1 shared A. Ploss· 1 shared A. R. Berneshawi· 1 shared A. Rutkowska· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. B. Balazs

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Macrophages govern antiviral responses in human lung tissues protected from SARS-CoV-2 infection

D. J. Kenney, A. K. O'Connell, J. Turcinovic, P. Montanaro, R. M. Hekman, T. Tamura, A. R. Berneshawi, T. R. Cafiero, S. Al Abdullatif, B. Blum, S. I. Goldstein, B. Heller, H. P. Gertje, E. Bullitt, A. J. Trachtenberg, , F. Douam

This study shows that macrophages mediate antiviral responses in human lung tissues, protecting against SARS-CoV-2 infection through the USP18-ISG15 axis.

bioRxiv · Jul 17, 2021 · PreprintMicrobiology

Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo

J. Perrin, T. Werner, N. Kurzawa, D. D. Childs, M. Kalxdorf, A. Rutkowska, D. Poeckel, D. C. Sevin, E. Stonehouse, K. Strohmer, B. Heller, D. Thomson, J. Vappiani, J. Krause, H. C. Eberl, , G. Bergamini

This study introduces tissue-TPP and blood-CETSA to measure proteome thermal stability, revealing organ physiology and drug-target engagement in vivo.

bioRxiv · Dec 20, 2018 · PreprintCell Biology