Cell BiologybioRxiv
Polycomb sustains promoters in a deep OFF-state by limiting PIC formation to counteract transcription
A. T. Szczurek, E. Dimitrova, J. R. Kelley, R. J. Klose
This study reveals that the Polycomb system sustains a deep promoter OFF-state by limiting PIC formation, thereby repressing transcription in single cells.
DOI 10.1038/s41556-024-01493-w