The pharmacokinetics and pharmacodynamics of 4-methylumbelliferone and its glucuronide metabolite in mice
N. Nagy, G. Kaber, N. Haddock, A. Hargil, J. Rajadas, S. Malhotra, M. Unger, A. Frymoyer, P. Bollyky
This paper investigates the pharmacokinetics and pharmacodynamics of 4-MU and its metabolite 4-MUG in mice, showing significant differences in exposure and bioavailability between administration routes.
bioRxiv · Aug 18, 2022 · PreprintPharmacology & Toxicology