Fast skeletal myosin binding protein-C expression exacerbates dysfunction in heart failure
J. McNamara, T. Song, P. Alam, A. Binek, R. Singh, M. Nieman, S. Koch, M. Ivey, T. Lynch, J. Rubinstein, J. P. Jin, J. Lorenz, J. Van Eyk, O. Kanisicak, S. Sadayappan
This study investigates the role of fast skeletal myosin binding protein-C in heart failure, finding that its expression exacerbates cardiac dysfunction and that its deletion improves heart function.
bioRxiv · Apr 30, 2024Physiology