BioengineeringbioRxiv
Chemical genomic guided engineering of gamma-valerolactone tolerant yeast
S. Bottoms, Q. Dickinson, M. McGee…·J. S. Piotrowski
The paper engineers a GVL-tolerant yeast strain by deleting PAD1 and FDC1, enhancing ergosterol content and improving fermentation in GVL-containing hydrolysates.
DOI 10.1186/s12934-017-0848-9