Author

J. Saba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

R. Landick· 4 shared R. A. Mooney· 2 shared T. V. Mishanina· 2 shared A. S. Garje· 1 shared B. A. Marshall· 1 shared D. Nayak· 1 shared F. Lan· 1 shared I. Artsimovitch· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersMicrobiology

R. Landick

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Author profile →

5 papers

Recent·Most cited

Bacteroides expand the functional versatility of a universal transcription factor and transcribed DNA to program capsule diversity

J. Saba, K. Flores, B. A. Marshall, M. D. Engstrom, Y. Peng, A. S. Garje, L. Comstock, R. Landick

The paper investigates how Bacteroides use the Y-Z regulatory system to control capsule polysaccharide (CPS) transcription and create subpopulations for fitness.

bioRxiv · Jun 21, 2024 · PreprintMicrobiology

Capabilities of the CCi-Mobile Cochlear Implant Research Platform for Real-Time Sound Coding

M. Azadpour, J. Saba, J. H. L. Hansen, M. A. Svirsky

This paper describes the CCI-Mobile platform for real-time sound coding in auditory implants and discusses its architecture and design considerations.

bioRxiv · Dec 8, 2022Bioengineering

Massively parallel single-cell sequencing of genetic loci in diverse microbial populations

F. Lan, J. Saba, T. D. Ross, Z. Zhou, K. Krauska, K. Anantharaman, R. Landick, O. S. Venturelli

This paper introduces DoTA-seq, a method for single-cell sequencing of genetic loci in microbial populations, and demonstrates its application in studying phase-variable operons and antibiotic resistance gene shifts.

bioRxiv · Nov 21, 2022 · PreprintMicrobiology

The elemental mechanism of transcriptional pausing

J. Saba, X. Chua, T. V. Mishanina, D. Nayak, T. A. Windgassen, R. A. Mooney, R. Landick

This study identifies the elemental pause mechanism in transcription by showing it is multipartite, causes a conformational shift, and can transition into backtracked states.

bioRxiv · Sep 19, 2018Biochemistry

Structural basis for transcript elongation control by NusG/RfaH universal regulators

J. Y. Kang, R. A. Mooney, Y. Nedialkov, J. Saba, T. V. Mishanina, I. Artsimovitch, R. Landick, S. Darst

This study determines the structural basis of how NusG and RfaH regulate transcript elongation by suppressing backtracking and pausing in bacterial RNA polymerase complexes.

bioRxiv · May 16, 2018Biophysics