Author

L. Comstock

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:ecology & biodiversity· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Basu· 1 shared A. Fiebig· 1 shared A. Krishnamohan· 1 shared A. M. Eren· 1 shared A. S. Garje· 1 shared B. A. Marshall· 1 shared B. Theriault· 1 shared C. B. Edgington· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMicrobiology

A. Basu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bacteroides expand the functional versatility of a universal transcription factor and transcribed DNA to program capsule diversity

J. Saba, K. Flores, B. A. Marshall, M. D. Engstrom, Y. Peng, A. S. Garje, L. Comstock, R. Landick

The paper investigates how Bacteroides use the Y-Z regulatory system to control capsule polysaccharide (CPS) transcription and create subpopulations for fitness.

bioRxiv · Jun 21, 2024 · PreprintMicrobiology

Untangling the Role of Pathobionts from Bacteroides Species in Inflammatory Bowel Diseases

Y. Shan, J. Lake, C. M. Cham, M. Zhu, D. Kaur, D. Ringus, N. Fei, C. R. Weber, M. Spedale, B. Theriault, S. Dalal, D. T. Rubin, A. Fiebig, S. Crosson, K. Lolans, , E. B. Chang

This study shows that Bacteroides fragilis from UC patients promotes colitis in genetically susceptible mice, suggesting a role for pathobionts in IBD.

bioRxiv · Oct 29, 2023 · PreprintMicrobiology

tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10

S. E. Strassler, I. E. Bowles, A. Krishnamohan, H. Kim, C. B. Edgington, E. G. Kuiper, C. J. Hancock, L. Comstock, J. E. Jackman, G. L. Conn

This study identifies that Trm10 substrate recognition depends on tRNA conformational changes induced by the enzyme, revealing a novel mechanism for tRNA modification.

bioRxiv · Feb 1, 2023Biochemistry