BiochemistrybioRxiv
Vibrio cholerae's ToxRS Bile Sensing System
N. Gubensaek, T. Sagmeister, C. Buhlheller…·T. Pavkov-Keller
This study reveals the crystal structure of ToxRS and its interaction with bile acids, showing ToxS's folded bile-binding pocket depends on ToxR and highlighting its conservation across Vibrio species.
DOI 10.7554/elife.88721