I. Uson

Vibrio cholerae's ToxRS Bile Sensing System

This study reveals the crystal structure of ToxRS and its interaction with bile acids, showing ToxS's folded bile-binding pocket depends on ToxR and highlighting its conservation across Vibrio species.

Model building in SHELXE

The paper describes improvements in SHELXE for model building through enhanced density modification and side chain tracing, enabling complete model solutions from partial data.

Exploring generality of experimental conformational changes with AlphaFold predictions

The paper uses AlphaFold predictions to explore conformational changes in LysR-type transcriptional regulators by comparing experimental structures with predicted models.

Fragment-based ab initio phasing of peptidic nanocrystals by MicroED

This paper introduces a fragment-based method for de novo structure determination of peptidic nanocrystals using MicroED, enabling the solution of previously intractable structures.

The Amphibian Antimicrobial Peptide Uperin 3.5 is a Cross-α/Cross-β Chameleon Functional Amyloid

This paper studies the formation of functional amyloid fibrils by the amphibian antimicrobial peptide uperin 3.5, showing its ability to switch between cross-α and cross-β structures under different conditions.

A conserved mechanism for meiotic chromosome organization through self-assembly of a filamentous chromosome axis core

The paper identifies conserved axis core proteins across species and shows they form filamentous structures essential for meiotic chromosome organization and recombination.