Author

J. Sears

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Benos· 2 shared A. Grenell· 2 shared B. Anand-Apte· 2 shared C. Singh· 2 shared A. N. Kettenbach· 1 shared D. Hanna· 1 shared H. Brunengraber· 1 shared H. E. Opalko· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

A. Benos

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The urea cycle is transcriptionally controlled by hypoxia-inducible factors

C. Singh, A. Benos, A. Grenell, V. Tran, D. Hanna, N. Kannekanti, B. Anand-Apte, H. Brunengraber, J. Sears

The paper shows that HIFs regulate urea cycle genes CPS1 and ARG1, leading to increased urea cycle activity in the liver under hypoxia.

bioRxiv · Jan 25, 2021 · PreprintBiochemistry

Hyperoxia inhibits proliferation of retinal endothelial cells in Myc dependent manner

C. Singh, A. Benos, A. Grenell, S. Rao, B. Anand-Apte, J. Sears

The paper shows hyperoxia inhibits retinal endothelial cell proliferation via Myc dependency, contributing to oxygen-induced retinopathy.

bioRxiv · Nov 9, 2020Cell Biology

Fission yeast Pak1 phosphorylates anillin-like Mid1 for spatial control of cytokinesis

J. O. Magliozzi, J. Sears, L. Cressey, M. Brady, H. E. Opalko, A. N. Kettenbach, J. B. Moseley

This study identifies Pak1 as a kinase that phosphorylates Mid1 to regulate cytokinesis in fission yeast by controlling CAR assembly and division plane positioning.

bioRxiv · Mar 10, 2020Cell Biology