Horizontal mitochondrial transfer from the microenvironment increases glioblastoma tumorigenicity
D. C. Watson, D. Bayik, S. E. Williford, A. Lauko, Y. Zhou, G. Deshpande, J. Seder, J. A. Mears, F. Cheng, A. B. Hjelmeland, J. D. Lathia
The paper identifies horizontal mitochondrial transfer from astrocytes to glioblastoma cells as a mechanism that enhances tumorigenicity by improving mitochondrial function and metabolic capacity.
bioRxiv · Sep 1, 2021Cancer Biology