Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes
C. Lancaster, A. Fountain, R. Dayam, E. Somerville, J. Sheth, V. Jacobelli, A. Somerville, M. Terebiznik, R. J. Botelho
This study shows that phagosome resolution through clathrin-dependent fragmentation regenerates lysosomes and maintains macrophage degradative capacity after multiple rounds of phagocytosis.
bioRxiv · May 14, 2020Cell Biology