Parallel CRISPR-Cas9 screens reveal mechanisms of PLIN2 and lipid droplet regulation
M. A. Roberts, K. K. Deol, M. Lange, D. E. Leto, A. J. Mathiowetz, J. Stevenson, S. H. Hashemi, D. W. Morgens, E. Easter, K. Heydari, M. A. Nalls, M. C. Bassik, M. Kampmann, R. R. Kopito, F. Faghri, J. A. Olzmann
The paper uses CRISPR-Cas9 screens to identify genes regulating PLIN2 and lipid droplet abundance, revealing new mechanisms and creating a resource for lipid metabolism research.
bioRxiv · Aug 27, 2022 · PreprintCell Biology