Author

J. Tyc

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:Drosophila· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

S. Vaughan· 4 shared J. Sunter· 3 shared M. Ahmed· 2 shared S. Dean· 2 shared S. Shafiq· 2 shared A. Hoffmann· 1 shared A. L. De castro neto· 1 shared A. Paterou· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersCell Biology

S. Vaughan

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5 papers

Recent·Most cited

Identification of 30 transition fibre proteins reveals a complex and dynamic structure with essential roles in ciliogenesis

M. Ahmed, R. J. Wheeler, J. Tyc, S. Shafiq, J. Sunter, S. Vaughan

The paper identifies 30 new transition fibre proteins in Trypanosoma brucei and shows their dynamic roles in ciliogenesis and flagellum length regulation.

bioRxiv · May 29, 2023 · PreprintCell Biology

Unlocking Trypanosome Biology: A Comprehensive Protein-Tagging Toolkit for Localization and Functional Analysis

A. Paterou, J. Tyc, J. Sunter, S. Vaughan, K. Gull, S. Dean

The paper expands a protein-tagging toolkit for trypanosomes with over 100 vectors, enabling flexible localization and functional analysis of proteins using diverse fluorescent and biochemical tags.

bioRxiv · Apr 21, 2023 · PreprintCell Biology

Massive accumulation of strontium and barium in diplonemid protists

J. Pilatova, D. Tashyreva, J. Tyc, M. Vancova, S. N. H. Bokhari, R. Skoupy, M. Klementov, H. Kupper, P. Mojzes, J. Lukes

This study identifies diplonemid protists as significant accumulators of strontium and barium, forming crystals that may influence oceanic mineral cycling and sedimentation.

bioRxiv · Jun 27, 2022Microbiology

A key regulatory protein for flagellum length control in stable flagella

M. Atkins, J. Tyc, S. Shafiq, M. Ahmed, E. Bertiaux, A. L. De castro neto, J. Sunter, P. Bastin, S. Dean, S. Vaughan

This paper identifies Cep164C as a key protein involved in maintaining stable flagellum length in Trypanosoma brucei by acting as a molecular lock at the flagellum base.

bioRxiv · Dec 11, 2019Cell Biology

A molecular model of the mitochondrial genome segregation machinery in Trypanosoma brucei

A. Hoffmann, S. Käser, M. Jakob, S. Amodeo, C. Peitsch, J. Tyc, S. Vaughan, B. Zuber, A. Schneider, T. Ochsenreiter

The paper uses super-resolution microscopy and biochemical analysis to show the hierarchical assembly of the TAC in Trypanosoma brucei, independent of the mitochondrial genome.

bioRxiv · Sep 20, 2017Cell Biology