CRISPR activation and interference screens in primary human T cells decode cytokine regulation
R. Schmidt, Z. Steinhart, M. Layeghi, J. W. Freimer, V. Q. Nguyen, F. Blaeschke, A. Marson
The paper uses CRISPR activation and interference screens in primary human T cells to identify cytokine regulators, finding genes like FOXQ1 that influence cytokine production and immune cell functions.
bioRxiv · May 11, 2021Immunology