R. Schmidt

Reduced accrual of mineral-associated organic matter after two years of enhanced rock weathering in cropland soils, though no net losses of soil organic carbon

This study evaluates the impact of enhanced rock weathering on soil organic matter pools over two years, finding reduced mineral-associated organic matter accrual without net losses of soil organic carbon.

Physiological responses to a changing winter climate in an early spring-breeding amphibian

This study examines how common toads respond physiologically to warmer winters and late spring freezes, finding increased energy expenditure and reduced cold tolerance in warmer-acclimated toads.

Intermittent water stress favors microbial generalists that better help wheat under drought

The paper shows that intermittent water stress history in soil selects for microbial generalists that enhance wheat's drought resistance.

Uncovering the Environmental Conditions Required for Phyllachora maydis Infection and Tar Spot Development on Corn in the United States for Use as Predictive Models for Future Epidemics

T helper cells exhibit a dynamic and reversible 3'UTR landscape.

The paper examines 3'UTR dynamics in T helper cells, finding that alternative polyadenylation (APA) events are transient and do not strongly correlate with differential gene expression.

Modular Pooled Discovery of Synthetic Knockin Sequences to Program Durable Cell Therapies

The paper develops ModPoKI, a platform for modular construction of DNA knockin libraries to identify gene constructs that enhance T cell function and persistence.

Assessment of 3D MINFLUX data for quantitative structural biology in cells revisited

The paper re-analyzes MINFLUX 3D imaging data to confirm its high localization precision and discuss its implications for structural biology.

Endoplasmic reticulum oxidoreductin (ERO) provides resilience against reductive stress and hypoxic conditions by mediating luminal redox dynamics

The paper demonstrates that EROs maintain ER redox homeostasis by integrating reductive and oxidizing inputs during hypoxia and reductive stress.

Visualization of bacterial type 3 secretion system components down to the molecular level by MINFLUX nanoscopy

The paper uses MINFLUX nanoscopy to visualize T3SS components at high resolution, revealing structural details of bacterial virulence factors.

ERM-1 phosphorylation and NRFL-1 redundantly control lumen formation in the C. elegans intestine

This study shows that ERM-1 and NRFL-1 work together to control intestinal lumen formation in C. elegans, with NRFL-1 compensating for ERM-1 phosphorylation defects.

CRISPR activation and interference screens in primary human T cells decode cytokine regulation

The paper uses CRISPR activation and interference screens in primary human T cells to identify cytokine regulators, finding genes like FOXQ1 that influence cytokine production and immune cell functions.

Local DNA shape is a general principle of transcription factor binding specificity in Arabidopsis thaliana

This paper uses DNA shape features to improve transcription factor binding prediction in Arabidopsis thaliana, showing that DNA shape enhances prediction beyond sequence alone.

Adaptive thermogenesis in mice requires adipocyte light-sensing via Opsin 3

This study shows that blue light sensed by OPN3 in adipocytes regulates thermogenesis and lipolysis in mice.

An adipocyte light-Opsin 3 pathway regulates the circadian clock and energy balance.

This study identifies a light-OPN3 pathway in adipocytes that regulates circadian rhythms, energy balance, and thermogenesis in mice.

Optogenetic dissection of mitotic spindle positioning in vivo

This study uses optogenetics to dissect mitotic spindle positioning in C. elegans embryos, showing that G-GTP signaling is dispensable and LIN-5Mud/NuMA activates dynein-dependent forces.