Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages
E. Yau, Y. Chen, C. Song, J. Web, M. Carillo, Y. I. Kawasawa, Z. Tang, Y. Takahashi, T. M. Umstead, S. Dovat, Z. C. Chroneos
This study investigates how the absence of the SP-R210L isoform in macrophages leads to a hyper-inflammatory state through altered genomic and epigenomic responses.
bioRxiv · Apr 2, 2021Immunology