Synthetic BiologybioRxivPreprint
A multiplexed, confinable CRISPR/Cas9 gene drive propagates in caged Aedes aegypti populations
M. A. E. Anderson, E. Gonzalez, M. P. Edgington…·L. Alphey
The paper tests a CRISPR/Cas9 gene drive in caged Aedes aegypti populations, showing it increases from 50% to 89% carrier frequency despite fitness costs.
DOI 10.1101/2022.08.12.503466