SARS-CoV-2 Variant Spike and accessory gene mutations alter pathogenesis
M. McGrath, Y. Xue, C. Dillen, L. Oldfield, N. Assad-Garcia, J. Zaveri, N. Singh, L. Baracco, L. Taylor, S. Vashee, M. Frieman
This study investigates how non-Spike mutations in SARS-CoV-2 variants affect pathogenesis and transmission, revealing that accessory gene mutations can lead to attenuating phenotypes.
bioRxiv · May 31, 2022Microbiology