Author

J.-C. Grenier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Organism:human· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Organism:chicken / avian· 1 Research Focus:ecology & biodiversity· 1 Approach:experimental assay· 1

Frequent Co-Authors

L. B. Barreiro· 3 shared V. Yotova· 3 shared A. Dumaine· 1 shared C. M. Bergey· 1 shared D. Fournelle· 1 shared D. J. Hamelin· 1 shared D. Jansen· 1 shared E. Archie· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersEvolutionary Biology

L. B. Barreiro

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Author profile →

4 papers

Recent·Most cited

Synchrony and idiosyncrasy in the gut microbiome of wild baboons

J. R. Bjork, M. R. Dasari, K. Roche, L. Grieneisen, T. J. Gould, J.-C. Grenier, V. Yotova, N. Gottel, D. Jansen, L. R. Gesquiere, J. B. Gordon, N. H. Learn, T. L. Wango, R. S. Mututua, J. K. Warutere, , E. Archie

This study examines gut microbiome dynamics in wild baboons, finding that microbial dynamics are largely idiosyncratic despite shared environments, with host-specific factors explaining most variation.

bioRxiv · Nov 24, 2021Ecology

The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA supertype-dependent manner

D. J. Hamelin, D. Fournelle, J.-C. Grenier, J. Schockaert, K. Kovalchik, P. Kubiniok, F. Mostefai, J. D. Duquette, F. Saab, I. Sirois, M. Smith, S. Pattijn, H. Soudeyns, H. Decaluwe, J. Hussin, E. Caron

This study analyzes SARS-CoV-2 mutations to show how they diversify T cell targets in an HLA supertype-dependent manner, leading to epitope loss in B7 supertype carriers.

bioRxiv · Jun 3, 2021Immunology

Primate innate immune responses to bacterial and viral pathogens reveals an evolutionary trade-off between strength and specificity

M. B. F. Hawash, J. Sanz-Remon, J.-C. Grenier, J. Kohn, V. Yotova, Z. Johnson, R. E. Lanford, J. F. Brinkworth, L. B. Barreiro

This study compares immune responses in apes and African and Asian monkeys to bacterial and viral pathogens, finding apes have stronger but less specific early immune responses.

bioRxiv · Jul 23, 2020Evolutionary Biology

Natural selection contributed to immunological differences between human hunter-gatherers and agriculturalists

G. F. Harrison, J. Sanz, J. Boulais, M. J. Mina, J.-C. Grenier, Y. Leng, A. Dumaine, V. Yotova, C. M. Bergey, S. J. Elledge, E. Schurr, L. Quintana-Murci, G. H. Perry, L. B. Barreiro

The paper compares transcriptional immune responses between hunter-gatherers and agriculturalists, finding greater divergence in viral response and evidence of natural selection in hunter-gatherers.

bioRxiv · Dec 4, 2018Evolutionary Biology