L. B. Barreiro

The paper identifies oxadiazole-based compounds that enhance anti-tuberculosis treatment by increasing host resistance through zinc poisoning of Mycobacterium tuberculosis.

The paper investigates the role of transposable elements in variable influenza infection responses by analyzing transcriptome and chromatin accessibility data from infected macrophages.

This study examines gut microbiome dynamics in wild baboons, finding that microbial dynamics are largely idiosyncratic despite shared environments, with host-specific factors explaining most variation.

Epithelial GATA4 regulates intestinal regionalization of bacterial colonization, metabolic pathways, and tissue immunity.

This study identifies lung epithelial signaling as critical for early vaccine-induced CD4+ T cell activation and Mtb control in BCG vaccinated hosts.

This study compares immune responses in apes and African and Asian monkeys to bacterial and viral pathogens, finding apes have stronger but less specific early immune responses.

The paper compares transcriptional immune responses between hunter-gatherers and agriculturalists, finding greater divergence in viral response and evidence of natural selection in hunter-gatherers.

This study analyzes the demographic history and mutational load of African hunter-gatherers and farmers using exome sequencing data, finding similar mutation loads despite differing demographic histories.