ImmunologybioRxivPreprint
NLRP3- and AIM2-autonomy in a mouse model of MSU crystal-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il-1 expression as relevant therapy for gout patients.
A. Mariotte, A. Decauwer, C. Po…·P. Georgel
This study uses a mouse model to investigate MSU crystal-induced inflammation and identifies imiquimod as a potential therapeutic target for gout by modulating IL-1 expression.
DOI 10.1101/772756