BiophysicsbioRxivPreprint
Cell fate determination by Lamarckian molecule-inheritance and chance
Frank J. Bruggeman, Jaap Schouten, Daan H. de Groot, Robert Planqué
The paper develops a theory to explain cellular heterogeneity by considering stochastic ancestral events in isogenic cell populations, showing that copy-number noise is unavoidable due to cell division stochasticity.
DOI 10.1101/618199