Cell BiologybioRxivPreprint
Genome-Wide CRISPRi Screening Identifies XPO5 as a Regulator of B Cell Mutation and Fitness
Tylar Kirch, Zachary D. Miller, Jacob S. Dearborn…·Devdoot S. Majumdar
This study identifies XPO5 as a regulator of B cell receptor surface expression through a genome-wide CRISPRi screen, showing its role in balancing mutagenesis and DNA repair during somatic hypermutation.
DOI 10.64898/2026.04.22.720139