Author

Jaisen Lim

University of California San Diego

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Neuroscience· 1

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

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Don W. ClevelandiD· 1 shared Haiyang Yu· 1 shared John R. YatesiD· 1 shared John RavitsiD· 1 shared Jolene K. DiedrichiD· 1 shared Lilian Gao· 1 shared Michael W. BaughniD· 1 shared Shan LuiD· 1 shared

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1 shared paperNeuroscience

Don W. ClevelandORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintSep 4, 2024

Acetylation of lysine 82 initiates TDP-43 nuclear loss of function by disrupting its nuclear import

Sitao Zhang, Sonia Vazquez‐Sanchez, Shan Lu…·Don W. Cleveland

This study identifies acetylation of lysine 82 in TDP-43 as a mechanism causing nuclear loss of function and cytoplasmic accumulation, linked to neurodegenerative diseases like ALS.

10 citations

humanproteomics

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