Cell BiologybioRxivPreprint
Inhibition of the Notch signaling pathway promotes AQP2 plasma membrane accumulation in renal epithelial cells by depolymerizing actin and reducing endocytosis
Asma Tchakal-Mesbahi, Huihui Huang, Jake Charles Ross…·Dennis Brown
This study shows that inhibiting Notch signaling increases AQP2 membrane accumulation in renal epithelial cells by reducing endocytosis and disrupting actin polymerization.
DOI 10.64898/2026.08.11.744289