Author

Jake Kircher

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Aaron P. HavasiD· 1 shared Adarsh RajeshiD· 1 shared Alessandra SaccoiD· 1 shared Allen WangiD· 1 shared Amirhossein Nayeri RadiD· 1 shared Ana Catarina FrancoiD· 1 shared Andrew Davis· 1 shared Angela LiouiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Aaron P. HavasORCID

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1 paper

Recent·Most cited

Targeting CyclinD1-CDK6 to Mitigate Senescence-Driven Inflammation and Age-Associated Functional Decline

Adarsh Rajesh, Aaron P. Havas, Rouven Arnold, Kathryn Lande, Xue Lei, Kelly Yichen Li, Armin Gandhi, Ana Catarina Franco, Seung‐Hwa Woo, Anthony B. Lagnado, Angela Liou, K. Garrett Evensen, Linshan Laux, Maggie Klaers, Jake Kircher, , Peter D. Adams

This study shows that targeting CCND1-CDK6 reduces DNA damage, inflammation, and age-related decline in mice by suppressing SASP and ISG expression.

Nature Aging · Aug 20, 2026Peer-reviewedCell Biology