Author

Seung‐Hwa Woo

Mayo ClinicORCID 0000-0002-9336-4457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Aaron P. HavasiD· 2 shared Adarsh RajeshiD· 2 shared Anthony B. LagnadoiD· 2 shared Armin GandhiiD· 2 shared Brightany Li· 2 shared Carolina Cano MacipiD· 2 shared João F. PassosiD· 2 shared Karl N. MilleriD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Aaron P. HavasORCID

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2 papers

Recent·Most cited

Cell BiologyNature AgingPeer-reviewedAug 20, 2026

Targeting CyclinD1-CDK6 to Mitigate Senescence-Driven Inflammation and Age-Associated Functional Decline

Adarsh Rajesh, Aaron P. Havas, Rouven Arnold…·Peter D. Adams

This study shows that targeting CCND1-CDK6 reduces DNA damage, inflammation, and age-related decline in mice by suppressing SASP and ISG expression.

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mouseexperimental assay

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Cell BiologyNature CommunicationsPeer-reviewedMar 5, 2025

Linked regulation of genome integrity and senescence-associated inflammation by p53

Karl N. Miller, Brightany Li, Hannah R. Pierce-Hoffman…·Peter D. Adams

This study identifies a mitochondria-regulated p53 circuit that links genomic instability and inflammation in senescent cells, showing p53 suppresses inflammation without affecting cell cycle arrest.

49 citationstop 1%

mouseDNA methylation

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