BiophysicseLifePeer-reviewed
A binding site for phosphoinositides described by multiscale simulations explains their modulation of voltage gated sodium channels
Yiechang Lin, Elaine Tao, James P Champion, Ben Corry
This paper uses multiscale simulations to show that PI(4,5)P2 binds to Nav channels, modulating their activity by affecting conformational changes and recovery from inactivation.
10 citations