Author

Jan P. Hummel

Harvard University

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Biology Disciplines

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Bioinformatics· 1

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Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Allen W. LynchiD· 1 shared Benedikt GeigeriD· 1 shared D. GulhaniD· 1 shared Hu JiniD· 1 shared Michael S. LawrenceiD· 1 shared Peter J. ParkiD· 1 shared S W LeeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Allen W. LynchORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintApr 21, 2026

Topographical archetypes of somatic mutagenesis in cancer

Allen W. Lynch, S W Lee, Jan P. Hummel…·Peter J. Park

The paper introduces MuTopia, a framework that identifies topographic archetypes of mutagenesis in cancer genomes, revealing that mutational processes are constrained by replication timing and chromatin state.

DOI 10.64898/2026.04.18.719374

humanwhole-genome sequencing

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