Systems BiologybioRxiv
Limiting the Development of Anti-Cancer Drug Resistance in a Spatial Model of Micrometastases
Ami B Shah, Katarzyna A Rejniak, Jana L Gevertz
This study uses a spatial model to show that certain fractionated-dose chemotherapy protocols are as effective as metronomic therapy in reducing micrometastases with acquired or pre-existing resistance.
DOI 10.3934/mbe.2016038