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Jane J. Rosin

Brigham and Women's Hospital

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

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Alexander J. RuthenburgiD· 1 shared Amanda J. KeplingeriD· 1 shared Jimmy EliasiD· 1 shared

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Molecular BiologybioRxivPreprintOct 4, 2024

The N-terminus of YY1 regulates DNA and RNA binding affinity for both the zinc-fingers and an unexpected nucleic acid binding domain

Jimmy Elias, Jane J. Rosin, Amanda J. Keplinger, Alexander J. Ruthenburg

This study identifies two RNA binding domains in YY1, including a newly discovered nucleic acid binding domain, and reveals autoinhibitory effects of the N-terminus on these domains.

DOI 10.1101/2024.10.04.616721

DNA methylationproteomics

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