Author

Janhavi Limaye

UCL Queen Square Institute of Neurology

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Anna MallachiD· 1 shared James M. StaddoniD· 1 shared Jennifer M. PocockiD· 1 shared John HardyiD· 1 shared Katharina CoskeriD· 1 shared Stephen J. NeameiD· 1 shared Thomas M. PiersiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Anna MallachORCID

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1 paper

Recent·Most cited

NeuroscienceScientific ReportsPeer-reviewedJun 25, 2021

Microglial signalling pathway deficits associated with the R47H TREM2 variant linked to AD indicate inability to activate inflammasome

Katharina Cosker, Anna Mallach, Janhavi Limaye…·Jennifer M. Pocock

The paper shows that the R47H TREM2 variant impairs microglial signaling and inflammasome activation, potentially contributing to Alzheimer's disease progression.

55 citationstop 5%

humanATAC-seq

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