Author

Jason D. Lieb

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Assay:ChIP-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Ivan P. G. MoskowitziD· 2 shared Kohta IkegamiiD· 2 shared Stefano SecchiaiD· 2 shared Kevin StruhliD· 1 shared Omar AlmakkiiD· 1 shared Yuko HasegawaiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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2 shared papersGenetics

Ivan P. G. MoskowitzORCID

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3 papers

Recent·Most cited

GeneticsDevelopmental CellPeer-reviewedMar 1, 2020

Phosphorylated Lamin A/C in the nuclear interior binds active enhancers associated with abnormal transcription in progeria

Kohta Ikegami, Stefano Secchia, Omar Almakki…·Ivan P. G. Moskowitz

114 citationstop 4%

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyGenome ResearchPeer-reviewedNov 15, 2019

Promoter-specific dynamics of TATA-binding protein association with the human genome

Yuko Hasegawa, Jason D. Lieb, Kevin Struhl

The paper measures TBP binding dynamics across the human genome using ChIP-seq and finds that TBP turnover varies among promoters and correlates with transcriptional activity and regulatory elements.

57 citations

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 30, 2018

Depolymerized lamins link nuclear envelope breakdown to mitotic transcriptional quiescence

Kohta Ikegami, Stefano Secchia, Jason D. Lieb, Ivan P. G. Moskowitz

This study identifies depolymerized LMNA as a mediator of mitotic transcriptional quiescence by linking nuclear envelope breakdown to transcriptional repression.

2 citations

humanDNA methylation

𝕏 PostBluesky