ImmunologybioRxivPreprint
RNA helicase DDX1 regulates germinal centre selection and affinity maturation by promoting tRNA ligase activity
Rachael Kimber, Sarah Ingelsfield, Michael Screen…·Claudia Ribeiro de Almeida
This study shows DDX1 promotes B-cell proliferation in germinal centres by enhancing mRNA translation through tRNA ligase activity, crucial for affinity maturation.
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