Evolutionary BiologyNaturePeer-reviewed
Tempo and mode of genome evolution in a 50,000-generation experiment
Olivier Tenaillon, Jeffrey E. Barrick, Noah Ribeck…·Richard E. Lenski
The paper analyzes 264 genomes from 12 Escherichia coli populations over 50,000 generations to study genome evolution dynamics and finds that most fixed mutations are beneficial, with neutral mutations accumulating at a constant rate.
DOI 10.1038/nature18959