Cancer BiologybioRxivPreprint
Single Nucleus Profiling Reveals Rewired Tumor-Immune-Stromal Cell Communication in Plasmacytoid Urothelial Carcinoma
Kathryn H Gessner, Siyao Liu, Mi Zhou…·William Y Kim
This study compares tumor-immune-stromal communication in plasmacytoid urothelial carcinoma (PUC) and conventional urothelial carcinoma (CUC) using single nucleus RNA sequencing and spatial transcriptomics, identifying distinct signaling patterns and potential therapeutic targets.