Systems BiologyGut MicrobesPeer-reviewed
Gut dysbiosis was inevitable, but tolerance was not: temporal responses of the murine microbiota that maintain its capacity for butyrate production correlate with sustained antinociception to chronic morphine
Izabella Sall, Randi L. Foxall, Lindsey C. Felth…·Cheryl A. Whistler
The paper identifies microbiota-driven butyrate production as a factor maintaining antinociception in mice resistant to morphine tolerance.
10 citations