NeuroscienceSciencePeer-reviewed
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Cryo-EM Structures of Amyloid-β 42 Filaments from Human Brain
Yang Yang, Diana Arseni, Wenjuan Zhang…·Michel Goedert
Cryo-EM shows brain-derived Aβ42 filaments adopt two related S-shaped protofilament folds: Type I dominates sporadic Alzheimer's, Type II familial Alzheimer's, other disorders and App^NL-F knock-in mice.