Author

Jennifer Shepard

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Biochemistry· 1

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Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Alison Mungenast· 1 shared Ashlee Marie Plummer-Medeiros· 1 shared Chen Xu· 1 shared Dongming QianiD· 1 shared Hyeong-wook Choi· 1 shared John Wang· 1 shared Kangkang SongiD· 1 shared Karen TenDyke· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperBiochemistry

Alison Mungenast

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintSep 7, 2023

The crystal and cryo-EM structures of PLCγ2 reveal dynamic inter-domain recognitions in autoinhibition

Young-Cheul Shin, Ashlee Marie Plummer-Medeiros, Alison Mungenast…·Yu Chen

The paper determines crystal and cryo-EM structures of PLCγ2 in autoinhibited states and bound to FGFR1 kinase domain, revealing dynamic inter-domain interactions in autoinhibition.

DOI 10.1101/2023.09.07.556539

humanprotein structure

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