Kangkang Song

This study presents cryo-EM structures of a circularly permuted group II intron, revealing the mechanism of the hydrolysis pathway and its regulation by branch point and splice site mutations.

The paper determines the structure of the portal vertex and neck complex in the hyperthermophilic phage Oshimavirus, revealing a pressure-sensitive mechanism for terminating DNA packaging and triggering tail attachment.

The paper determines the 3D structure of mouse radial spoke 3 (RS3) using cryo-EM and identifies its role as a metabolic and regulatory hub in ciliary motility.

This study uses cryo-electron tomography to show that sialic acid binding causes influenza HA trimers to cluster and form triplets on virions.

This study identifies a cold-induced conformation of respiratory complex CI:III2 using cryo-EM and simulations, revealing structural changes that enhance electron transfer efficiency in cold environments.

The paper determines crystal and cryo-EM structures of PLCγ2 in autoinhibited states and bound to FGFR1 kinase domain, revealing dynamic inter-domain interactions in autoinhibition.

A hybrid cryo-electron microscopy method reveals subcellular structures at unprecedented resolution.