GenomicsInvestigative Opthalmology & Visual SciencePeer-reviewed
AAV-mediated CRISPR/Cas gene editing of retinal cells in vivo.
Sandy SC Hung, Vicki Chrysostomou, Amy Fan Li…·Alex Hewitt
This study uses AAV2 to deliver CRISPR/Cas components to retinal cells in Thy1-YFP mice, achieving an 84% reduction in YFP-positive cells without affecting retinal function.
DOI 10.1167/iovs.16-19316