Author

Jessica Sims

System Biosciences (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Alex A. PolleniD· 1 shared Alex RogozhnikoviD· 1 shared Andy Lash· 1 shared Anthony Batarse· 1 shared Anthony Bosshardt· 1 shared Anwesha DeyiD· 1 shared Arden B. PiephoiD· 1 shared Austin McKay· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Alex A. PollenORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 4, 2026

Preclinical Characterization of Hippo pathway inhibition: Insights from Pharmacological and Genetic Studies

Sayantanee Paul, Michelle L. Lepherd, Thijs J. Hagenbeek…·Anwesha Dey

This paper investigates the effects of Hippo pathway inhibition through pharmacological and genetic approaches, identifying kidney, pancreas, and thymus as target organs with dose-dependent toxicities.

DOI 10.64898/2026.08.01.742182

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 26, 2020

Optimization and scaling of patient-derived brain organoids uncovers deep phenotypes of disease

Kevan D. Shah, Rishi Bedi, Alex Rogozhnikov…·G. Sean Escola

This paper develops an automated system to scale patient-derived brain organoids, revealing consistent donor and batch effects and demonstrating reproducible disease phenotypes in tuberous sclerosis models.

10 citations

humanmachine learning (classical)

𝕏 PostBluesky