Evolutionary BiologymBioPeer-reviewed
Transcriptome remodeling contributes to epidemic disease caused by the human pathogen Streptococcus pyogenes
Stephen Beres, Priyanka Kachroo, Waleed Nasser…·James Musser
This study identifies horizontal gene transfer events in Streptococcus pyogenes that led to a more virulent genotype, causing epidemic disease through transcriptome remodeling and altered host-pathogen interactions.
DOI 10.1128/mbio.00403-16