ImmunologybioRxivPreprint
TridentTCR: Predicting T Cell Receptor Specificity for Antigens and Autoimmune-Related Targets via a Topology-Aware Graph and Large Language Model
Rui Niu, Xiaoying Kong, Ji-Ren Zhou…·Xuequn Shang
TridentTCR predicts TCR specificity for antigens and autoimmune targets using a graph neural network and large language model, achieving better classification and identifying cross-reactivity in type 1 diabetes.
DOI 10.1101/2025.06.27.661632