An Integrated Knowledge Graph and Network Medicine Pipeline for Drug Repurposing: Benchmarking Across Human Diseases and Application to Amyotrophic Lateral Sclerosis
Anqi Jiang, Jiajing Hu, Yusuf Abdulle…·Alfredo Iacoangeli
This paper presents a drug repurposing pipeline that integrates knowledge graphs and network medicine, benchmarked across diseases and applied to ALS, identifying 77 prioritized candidate drugs.