Author

Jiangbo Tong

Yangzhou University

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Pathology· 1

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Approach:deep learning· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Dan Liang· 1 shared Dongmei Hou· 1 shared Jian‐Ke TieiD· 1 shared Jinlin Huang· 1 shared Kang Liu· 1 shared Luju Chen· 1 shared Minwen Hong· 1 shared Nan JiangiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperPathology

Dan Liang

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PathologybioRxivPreprintFeb 18, 2025

Structural and Functional Insights into GGCX-FIX Interaction: Implications for Vitamin K-Dependent Bleeding Disorders

Kang Liu, Shixin Li, Jiangbo Tong…·Zhenyu Hao

This study identifies key functional regions of GGCX and their interactions with FIX using AlphaFold 3 and simulations, revealing residues critical for carboxylation and vitamin K epoxidation.

DOI 10.1101/2025.02.18.638829

humanprotein structure

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