GenomicsiSciencePeer-reviewed
Remodelling of the endothelial cell transcriptional program via paracrine and DNA-binding activities of MPO
Ruiyuan Zheng, Kyle Moynahan, Theodoros Georgomanolis…·Yulia Kargapolova
This study shows MPO enters endothelial cell nuclei, binds chromatin non-enzymatically, and regulates EndMT and EC fate through chromatin remodeling and interaction with ILF3.
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