NeurosciencebioRxivPreprint
Amelioration of signalling deficits underlying metabolic shortfall in TREM2R47H human iPSC-derived microglia
Foteini Vasilopoulou, Thomas M. Piers, Jingzhang Wei…·Jennifer M. Pocock
This study investigates how metabolite supplementation affects metabolic and functional deficits in TREM2-mutant human iPSC-derived microglia, identifying distinct effects of citrate and succinate on mitochondrial function and phagocytosis.
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